All I had to do was to upload my ancestry data that I already had. What they found was a game-changer: my genes were preventing the prescribed drugs from being effective. Armed with this information, my doctor was able to choose a medication that worked with my genetic makeup.
Susan, MoodNote Genomics Customer
customer feedback, promotions, questions ABOUT ALZHEIMER's
From Our Customers - Real Results, Real People
From Our Customers - Real Results, Real People
From Our Customers - Real Results, Real People
Susan, age 55
"I had been struggling with finding the right pain medication for what felt like forever. Whatever my doctor prescribed either didn't work, or gave me side effects I couldn’t tolerate. It was frustrating and disheartening, especially when everyone seemed to suggest that it was my fault, or that I was being a complainer.
When I read that my genes might be affecting how I respond to medications, I decided to look into it. That's when I discovered MoodNote Genomics. They were fantastic from the start. All I had to do was to upload my ancestry data that I already had.
What they found was a game-changer: my genes were preventing the prescribed drugs from being effective. Armed with this information, my doctor was able to choose a medication that worked with my genetic makeup. The difference has been incredible. For the first time in years, I feel like myself again.
MoodNote Genomics helped me finally find the right treatment. Their service was easy, affordable, and, most importantly, it worked. If you're having trouble with your medications, I highly recommend giving them a try."
E.B. age 65
"I was always looking for something new to help with my migraines because no matter what medications I tried, I ended up with side effects. I hated the upset stomachs, dizziness, and drowsiness almost as much as I hated the migraines. After someone suggested that maybe my problem was related to my genes, I started looking for companies that could investigate this. MoodNote Genomics was exactly what I was looking for. For a very reasonable price, they had me do a simple cheek swab to collect my genetic material for analysis and then interpreted the raw data for me.
What they found was that I have a mutation in a gene needed to process folic acid. They explained to me that folic acid is a nutrient important for many functions, including blood flow in the brain, heart health, and mood. Even though I had plenty of folic acid in my diet, I was unable to make use of it without this gene. They told me about a specific over-the-counter supplement that would bypass this mutation and provide my body with the folic acid it needed. Since I started taking this supplement, I have not had a single migraine. I am so grateful that I found MoodNote Genomics—they were able to provide an explanation and a simple solution for a problem I had been struggling with for years."
Promotions
From Our Customers - Real Results, Real People
From Our Customers - Real Results, Real People
We have a Winter Sale of pharmacogenetic (PGx) data interpretation and reporting. Please inquire.
If you have medical or emotional problems that evaded treatments, had unusual reactions to medications, or had genetic testing done and would like to know what the results mean, do not delay - contact us today!
Alzheimer's Disease Risk Determination
From Our Customers - Real Results, Real People
Alzheimer's Disease Risk Determination
Genomics of Alzheimer's disease has been studied intensely with the most studied gene being APOE. These are the questions that customers ask most frequently.
Is Alzheimer's disease genetic?
Alzheimer's disease can be influenced by both genetic and environmental risk factors.
Genetic factors are small variations in genetic code called Single Nucleotide Polymorphisms or SNPs (pronounced "snips"). These small changes may be responsible for a significant increase in Alzheimer's disease risk.
Environmental factors that increase the disease risk are depression, certain medications like Xanax, alcohol, lack of sleep or insufficient vitamin or hormone levels in your body.
Genetic risk factors
SNPs in the gene called APOE (or apolipoprotein E) are strongly associated with Alzheimer's disease. Depending on their combination the disease risk could be low, moderate, high or very high. For example, a combination known as e3/e3 occurs in approximately 66% of people and carries a moderate disease risk. Combinations that include e4 such as e3/e4 and e4/e4 increase Alzheimer's risk by approximately 3 to 35 times compared to e3/e3. The e2/e2 carriers are at a lower risk than most people but this combination occurs only rarely. Overall, there are are 6 possible combinations of APOE gene and each carry a different level of genetic risk for Alzheimer's dementia.
Is it possible to prevent or delay Alzheimer's?
Studies show that losing excess weight, stopping smoking and exercising regularly will significantly reduce Alzheimer's disease risk. Surprisingly, individuals who are e4 allele carriers and are at an increased risk for Alzheimer's, tend to benefit more from these simple health steps. This fact alone is a good reason to learn about your genetic makeup.
Remarkably, e4 carriers could experience mild memory loss even before they are diagnosed with Alzheimer's. However, if your genetic risk is low and you have memory problems, these problems could be caused by depression, certain medications like Xanax, or alcohol, lack of sleep, insufficient vitamin or hormone levels in your body. These are treatable conditions and should be discussed with your doctor without delay.
Planning for the future
Another good reason for knowing your genetic makeup and Alzheimer's genetic risk is additional time and opportunity that this information provides for making important decisions about your property, your family and your future care.
There are many genetic tests available today but interpretation of tests requires specialized knowledge and may not be available everywhere. We specialize in genetic data interpretation to provide actionable, physician-ready reports. If you are experiencing memory difficulties for have a family history of Alzheimer's, make an appointment with our specialists today!
Copyright © 2024 MoodNote LLC - All Rights Reserved
MoodNote Service is not a medical service. Information that is accessible through MoodNote webpages is not intended to diagnose, prevent or treat any disease or condition. MoodNote’s annotation of DNA variants is intended for educational and informational purposes only. Only a trained and duly licensed health care professional, after having conducted a thorough and direct examination, can diagnose or treat an emotional, psychological, psychiatric, neurological or medical condition. If you have any concerns about your health, please contact a qualified health care professional who is duly licensed in your jurisdiction. If you feel suicidal or have a medical emergency, please call 911 (in the US or Canada) or proceed to the nearest emergency room.