Impact of pharmacogenetics on your treatment results

MoodNote Genomic Analysis offers DNA data analysis, reanalysis, interpretation and specialist referral services. It also offers pharmacogenetics service.  

Our algorithm is highly accurate and has been validated. To validate the algorithm, we compared the presence of disease-related genes in about 200 cases of one disease and over 100 cases of another disease. The testing revealed an algorithm sensitivity of 89.6%, specificity of 88.3%, and accuracy of 89.1%.

What does this mean? Sensitivity refers to how well the algorithm identifies disease-related genes in patients who actually have the disease, while specificity measures how well it avoids falsely identifying these genes in people who don't have the disease. Accuracy reflects the overall reliability of the algorithm in making correct predictions. These high percentages mean the algorithm performs exceptionally well in distinguishing between diseases, ensuring precise and reliable results.

Our data sources are publicly accessible and highly reputable databases such as ClinVar, National Library of Medicine database of pathogenic and drug response variants, PharmGKB, Stanford University curated database of pharmacogenetic variants and many others. More information on specific databases and the pipeline of the variant discovery can be found in the Science section of this website.

Pharmacogenetic analysis reporting based on ancestry services data will be available in 24-48 hours upon our receipt of your data. DNA sequencing data provided in either VCF, BAM or FASTQ formats will be processed in about one week or less. Orders requiring DNA sequencing and subsequent data analysis will be completed in about 2-6 weeks. Expedited service options are available as well.

Yes, we can. It is important to keep in mind that the ancestry testing platforms are designed to identify only a very small number of variants, which may be associated with an individual's geographic ancestry. If you have your raw ancestry data file, you can upload your data to this website for interpretation and reporting on Pharmacogene and Alzheimer's genetic risk. Please follow this link for pricing and upload instructions. Registration and account activation is required.

Some services e.g. pharmacogenetic data analysis and interpretation may be covered by insurance plans. In order to protect our customer privacy we do not share their genetic data with insurance companies. Please follow this link for information on how genetic testing could affect your insurance.

In general, the Moodnote Clinical Genomics services should be eligible as medical care covered by your FSA/HSA benefit. Please inquire with your tax advisor or the department of your organization responsible for your benefits.

As an online service, MoodNote is accessible at any time for data upload.