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Known Risks Associated With Genetic Testing

There are risks associated with genetic testing and DNA data analysis. They are briefly summarized below. 


  • Uncertain Variants or Unanticipated Results


Genetic testing can sometimes reveal variants of uncertain significance, leading to ambiguous results that complicate clinical decision-making.


  • False Negatives and Positives


There is a risk of receiving false negative or positive findings, which could lead to misinformed health management decisions


  • Lack of Established Management Guidelines


For some conditions, there may be an absence of clear guidelines on how to best manage or treat the condition, leaving patients and healthcare providers in a challenging position.


  • Unpredictability of Future Health


While genetic testing can provide risk assessments for certain conditions, it cannot predict future health outcomes with certainty, leaving an element of unpredictability.


  • Emotional Impact


The knowledge gained from genetic testing can cause anxiety, stress, or emotional distress, impacting mental health.


  • Family Dynamics


Discovering genetic information can sometimes lead to feelings of blame, guilt, or secrecy within families, affecting relationships.


  • Discrimination Concerns


Individuals may have concerns about genetic discrimination in areas like employment or insurance, despite legal protections.


For those seeking more information on protections against genetic discrimination, the Genetic Information Nondiscrimination Act (GINA) provides a legal framework. It’s advisable to consult a discussion guide on GINA to understand your rights and the protections it offers.


Please contact MoodNote if you have questions, would like to place a data interpretation order or would like to schedule an appointment with a genomics-trained physician. Follow the link below to learn more about GINA. Please keep in mind that following this link will take you out of MoodNote's website.


Learn about GINA

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MoodNote Service is not a medical service. Information that is accessible through MoodNote webpages is not intended to diagnose, prevent or treat any disease or condition. MoodNote’s annotation of DNA variants is intended for educational and informational purposes only. Only a trained and duly licensed health care professional, after having conducted a thorough and direct examination, can diagnose or treat an emotional, psychological, psychiatric, neurological or medical condition. If you have any concerns about your health, please contact a qualified health care professional who is duly licensed in your jurisdiction. If you feel suicidal or have a medical emergency, please call 911 (in the US or Canada) or proceed to the nearest emergency room. 


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